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Title Slide 00:00:00 Outline of Presentation 00:01:39 Physics and Biological Problems 00:02:20 Philosophical Approaches? 00:03:38 Key Issues: Sensor and System 00:07:37 Sensing/Detection in Biology 00:08:55 Why Nanoscale Science and Technology? 00:10:17 Vision of Nanotechnology: A Bottom-Up Paradigm 00:11:13 Molecular Scale Nanowires 00:12:56 Silicon Nanowire Field Effect Transistors 00:14:00 Nanowire Nanosensors 00:15:40 Nanowire Nanosensors (cont.) 00:16:39 Nanowire Nanosensors (cont.) 00:17:45 Nanowire Nanosensors (cont.) 00:18:29 Nanowire pH Sensors 00:18:45 Detecting Ligand-Receptor Binding 00:19:39 Real-Time Detection of Proteins 00:20:56 Picking a Problem: Prostate Cancer 00:22:18 Nanowire Nanosensor: Real-Time Cancer Marker Detection 00:23:35 Nanowire Nanosensor: Real-Time Cancer Marker Detection 00:23:53 Sensor Arrays 00:24:40 Real-Time Multiplexed Detection with Nanowire 00:25:06 Parallel Detection and Diagnosis of Viruses Using Integrated Nano 00:25:25 Towards the Future: Areas to Impact 00:25:50 Enabling Personalized Medicine 00:26:03 Ultimate Sensor: Single-Molecule Detection 00:27:57 Estimating Nanowire Sensitivity 00:28:50 Nanowire Single-Molecule Electrical Detection? 00:29:31 Stochastic Sensing of Single Agents: The Need for Integrated Procesing 00:30:02 Sensing-Computation Duality at the Nanoscale 00:31:12 Processing: Today and Future 00:32:19
