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Experimental evolution with bacteria and digital organisms 00:00:00 Outline of talk 00:00:51 Experimental evolution with bacteria and digital organisms 00:01:07 Outline of talk 00:01:09 William Paley, Natural Theology (1802) 00:01:10 Paley, continued 00:01:43 Charles Darwin, On the Origin of Species (1859) 00:02:20 Darwin, continued 00:03:04 Some approaches to studying evolution 00:03:35 Question: How repeatable is evolution? 00:05:02 00:06:04 A billion mutations in each evolving population 00:07:02 Fitness trajectories 00:08:59 Cell size trajectories 00:10:33 Ecological specialization and catabolic breadth 00:10:56 Changes in gene expression using microarrays 00:12:10 00:16:27 Sequencing randomly chosen genes 00:17:39 Paley (1802) 00:18:28 00:20:21 00:21:11 00:22:30 They have genomes, metabolisms, and neighbors 00:23:19 And they evolve from a common ancestor into many species (kinds) 00:23:44 00:24:26 00:25:54 00:27:13 00:28:39 00:32:31 00:33:50 Replaying life s tape 00:35:55 00:36:36 Some readings for those interested 00:36:57